Ethylene and auxin crosstalk that regulates root development and gravitropism
The individual roles of auxin and ethylene in controlling the growth and development of young seedlings have been well studied. In recent years, these two hormones have been shown to act synergistically to control specific growth and developmental processes, such as root elongation and root-hair formation, as well as antagonistically in other processes, such as lateral-root formation. We have examined the interactions between these two hormones in lateral root development and find that ethylene inhibits lateral root development through modulation of auxin transport in both Arabidopsis and tomato. We have examined the distinct and overlapping transcriptional networks which control the response of roots to these two hormones using time course transcriptomics. We have also examined the ability of these two hormones to modulate root gravitropism by controlling levels of flavonol antioxidants.
Harkey, AF, Watkins, JR, Olex, AL, DiNapoli, KT, Lewis, DR, Fetrow, JS, Binder, BMc, and Muday, GK (In review) Identification of transcriptional and receptor networks that control root responses to ethylene using time course transcriptomics. Plant Physiology.
**Muday, GK, Maloney, GS, and Lewis, DR (2014) Integration of ethylene and auxin signaling and the developmental consequences of their crosstalk. In Ethylene in Plants. C-K Wen, ed. Springer, pp 175-204
**Muday, GK and Lewis, DR (2013) Ethylene regulates root growth and development. In Plant Roots: The Hidden Half. Eschel, A, Beeckman, T eds. Taylor and Francis Group, Boca Raton, pp 15:1-27
Lewis, DR, Olex, AL, Lundy, SR, Turkett, WH, Fetrow, JS, and Muday, GK (2013) A Kinetic Analysis of the Auxin Transcriptome Reveals Cell Wall Remodeling Proteins that Modulate Lateral Root Development in Arabidopsis. Plant Cell; 25: 3329-3346.
**Muday, GK, Rahman, A, Binder, BM (2012) Auxin and ethylene: Collaborators or Competitors? Trends in Plant Science, 17: 181-195.
Lewis, DR, Negi, S, Sukumar, P, Muday, GK (2011) Ethylene inhibits lateral root development and enhances IAA transport by altered expression and localization of auxin transport proteins. Development 138: 3485-3495.
Lewis, DR, Ramirez, MV, Valbuena, P, Miller, ND, Keith, R, Helm, R, Winkel, BSJ, Muday, GK (2011) Auxin and ethylene induce distinct flavonol accumulation patterns through independent transcriptional networks: Plant Physiol. 156: 144-164
Negi, S, Sukumar, P, Liu, X, Cohen, JD, and Muday, GK (2010) Genetic dissection of the role of ethylene in regulating auxin dependent lateral and adventitious root formation in tomato. Plant Journal 61: 3-15
Negi, S, Ivanchenko, MG, and Muday, GK (2008) Ethylene regulates lateral root formation and auxin transport in Arabidopsis thaliana. Plant J. 55: 175-187
Ivanchenko, MG, Muday, GK, and Dubrovsky, JG. (2008) Ethylene-auxin interactions regulate lateral root initiation and emergence in Arabidopsis thaliana. Plant J. 55: 335-347