Patricia C. Dos Santos

Patricia C. Dos Santos

Contact Info

Patrcia Dos Santos

Associate Professor

B.S., 1999, Universidade Federal do Rio Grande do Sul (Porto Alegre, Brazil)
Ph.D., 2004, Virginia Tech
Postdoctoral Associate, 2005-2008, Virginia Tech (Dennis Dean)

Office: Wake Downtown, Rm. 2818
Phone: (336) 702-1944
Email: dossanpc@wfu.edu

Web Site: http://college.wfu.edu/chemistry/research/dossantoslab/

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Research Description

Description of Research
Iron and sulfur atoms can form chemical structures of biological importance named [Fe-S] clusters.  The importance of Fe-S clusters is intimately associated with the essential role of Fe-S proteins in a wide range of life sustaining processes including respiration, carbon metabolism, photosynthesis and nitrogen fixation.  These chemical structures are organized in fundamental units of [2Fe-2S] and [4Fe-4S] clusters, or multimers, or fragments of these units.  Although [Fe-S] clusters can be formed in vitro from their toxic individual components, almost all forms of life have developed specialized machineries dedicated to the assembly of these metal-centers.  Our research group is interested in understanding the biochemical formation of [Fe-S] clusters in Gram-positive bacteria.

 

Publications

Awards & Accomplishments

NSF CAREER Award 2011-2016
Z. Smith Reynolds Foundation Faculty Fellowship 2013
Faculty Excellence in Research Award, WFU 2013
Outstanding Recent Alumna of the College of Agriculture and Life Science, Virginia Tech,2010