Welcome to the web page of the Microscopic Imaging Core Facility of the Biology Department at Wake Forest University. Here you can learn about our facility, our image capture and analysis capabilities, find operating protocols for our equipment, review technical documentation, and local users may reserve time on a system using our web-based calendar.

James Privitt Defends Thesis

by July 27, 2017
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    This week James Privitt defended his thesis and passed!  If you see him, please congratulate him.  James did his thesis work under Dr. Susan Fahrbach (lab page) and was an extensive user of the LSM 710 on the Reynolda campus.  In the fall he will be starting a Read more »

What is Airyscan?!

by June 27, 2017 » Add the first comment.

In January, we added the LSM 880 confocal microscope to our facility.  Everyone has loved the extra sensitivity and the crisp images that they have been getting from the new system.  There is a feature that many don’t know about, though.  The Airyscan detector! A new detector, how could that Read more »

New Microscopy Manager at Wake Downtown

by May 23, 2017
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Welcome to Dr. Heather Brown-Harding, our new microscopy manager stationed in the Wake Downtown Microscopy facility. Heather received her Ph.D. in Microbiology and Immunology from the University of Florida in 2013. Before joining us, she served as a Key Account Manager for Zeiss Microscopy in the greater Boston area. With Read more »

Wake Downtown Microscopy Facility

by February 6, 2017
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An entirely new microscopy facility is now open in room 2806 of Wake Downtown. This facility features an all new Zeiss 880 confocal with Airyscan, and a V-16 macroview microscope. Drop by to tour the equipment and discuss possible experimental and teaching applications, or make an appointment with the director Read more »

Primostar Student Microscopes with Green Fluorescence

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New student microscopes now available for Biology upper division teaching exercises. Zeiss Primostar compound microscopes include phase contrast and color digital cameras. Three Primostar microscopes feature push button LED green channel fluorescence, courtesy of the Biology Neuroscience Program.  An additional Primostar microscope is available without fluorescence, but featuring a wider variety Read more »

Compresstome Tissue Sectioning Device Now Available

by August 10, 2015
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The Compresstome tissue sectioning device offers an alternative to vibratome slicing, and features superior tissue block support and sectioning in the range of 30-500um thickness. This technique is suitable for live or fixed, non-frozen tissues. .

Fungi confocal images now integrated into a Citizen Science public game

by August 14, 2014

Sabrina Setaro and colleagues have created a Citizen Sort game that is now open to the public. After collecting a series of confocal image stacks of fluorescently stained fungi on various plant roots, this group seeks to utilize the power of citizen science to analyze and validate this large volume Read more »

Now Featuring: Imaris 3-D image manipulation and measurement software

by June 10, 2014

Imaris software is now in use that allows advanced 3-D reconstruction, viewing, and presentation of image stacks. Rendered images can be visualized and manipulated in standard mode, or as surface/contour plots. A host of analytic segmentation and measurement tools are also available.

HCImage software now available for image acquisition

by January 8, 2014

Hamamatsu HCImage capture and analysis software has been added for the Zeiss AxioObserver inverted fluorescent microscope. HCImage includes real-time image analysis features, an intuitive control module for acquisition settings, and advanced analysis paradigms such as ratiometric calculation and display. This software is intended as a replacement for the Volocity acquisition system.

Improved 10X Lens for Confocal Microscope System

by December 16, 2013

The confocal microscope has been upgraded with a new 10X 0.45 NA Plan Apo lens. This lens will substantially improve image quality for lower magnification acquisition.